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Typical research protocol framing (not a prescription): Sermorelin and ipamorelin are often described in research contexts as separate subcutaneous injections given simultaneously or within minutes of each other, typically at bedtime to coincide with the endogenous GH pulse and low somatostatin tone

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It's this paternalistic model, and that's how I was trained, which is, you're going to do this because I'm going to tell you to do it